Use of alpha-2I selective adrenergic receptor agonists in memory

Details Use of alpha-2I selective adrenergic receptor agonists in memory Use of alpha-2I selective adrenergic receptor agonists in memory

1986-11-07

1989-07-11

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

A61K 31165

Patent

active

048473006

ABSTRACT:
Disclosed is a method of treating memory disorders and cognitive decline, e.g., age-related cognitive decline, in a primate by administering thereto a therapeutically effective amount of an alpha-2 agonist having a high affinity for the alpha-2I subtype, e.g., guanfacine and guanabenz or a nontoxic, pharmaceutically acceptable salt thereof. Particularly preferred is the use of alpha-2I selective agonists such as guanfacine.

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