Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Method of regulating cell metabolism or physiology
Reexamination Certificate
2006-04-21
2011-11-01
Kim, Taeyoon (Department: 1651)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Method of regulating cell metabolism or physiology
C435S325000, C435S366000, C435S395000, C435S455000, C424S093210, C424S093700
Reexamination Certificate
active
08048673
ABSTRACT:
Methods and compositions for directing adipose-derived stromal cells cultivated in vitro to differentiate into cells of the chondrocyte lineage are disclosed. The invention further provides a variety of chondroinductive agents which can be used singly or in combination with other nutrient components to induce chondrogenesis in adipose-derived stromal cells either in cultivating monolayers or in a biocompatible lattice or matrix in a three-dimensional configuration. Use of the differentiated chondrocytes for the therapeutic treatment of a number of human conditions and diseases including repair of cartilage in vivo is disclosed.
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Gimble Jeffrey M.
Halvorsen Yuan-Di C.
Wilkison William O.
Artecel Sciences, Inc.
Kim Taeyoon
Seed IP Law Group PLLC
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