Use of adenosine antagonists in the treatment of bradyarrhythmia

Drug – bio-affecting and body treating compositions – Antiarrhythmic

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A61K 4700

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049803794

ABSTRACT:
A method to enhance the efficacy of cardioversion, defibrillation, cardiac pacing, and cardiopulmonary resuscitation and to treat post-resuscitation asystole, bradyarrhythmias, electromechanical dissociation, and hemodynamic collapse by administering to a human or animal an effective amount of an adenosine antagonist that competitively inhibits adenosine or that reduces the level of adenosine present in myocardial and vascular tissues and associated fluids.

REFERENCES:
Rahimtoola, S. H., J. Am. Med. Assoc., 247 pp. 2485-2890 (1982).
Iseri, L. T., Am. Int. Med. 88 pp. 741-745, 1978.

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