Surgery – Diagnostic testing – Cardiovascular
Reexamination Certificate
2006-09-12
2006-09-12
Bockeman, Mark (Department: 3766)
Surgery
Diagnostic testing
Cardiovascular
C607S025000
Reexamination Certificate
active
07107093
ABSTRACT:
A system and method for monitoring electrical dispersion of the heart is provided including an implantable medical device and associated electrode system for sensing cardiac signals from a combination of two or more local and/or global EGM sensing vectors and/or subcutaneous ECG sensing vectors. Activation and recovery times and the activation-recovery intervals are measured from a selected cardiac cycle for each sensing vector. Dispersion is determined as the differences between activation times, recovery times and/or ARIs measured from each of the sensing vectors. An increase in dispersion indicates a worsening of heart failure and/or an increased risk of arrhythmias. Accordingly, a cardiac therapy may be delivered or adjusted in response to a detected increase in dispersion.
REFERENCES:
patent: 4550502 (1985-11-01), Grayzel
patent: 4569357 (1986-02-01), Sanz et al.
patent: 5117824 (1992-06-01), Keimel et al.
patent: 5257621 (1993-11-01), Bardy et al.
patent: 5313953 (1994-05-01), Yomtov et al.
patent: 5560368 (1996-10-01), Berger
patent: 5560370 (1996-10-01), Verrier et al.
patent: 5792065 (1998-08-01), Xue et al.
patent: 5987352 (1999-11-01), Klein et al.
patent: 6070101 (2000-05-01), Struble et al.
patent: 6152882 (2000-11-01), Prutchi
patent: 6438409 (2002-08-01), Malik et al.
patent: 6456880 (2002-09-01), Park et al.
patent: 6466819 (2002-10-01), Weiss
patent: 6473645 (2002-10-01), Levine
patent: 6522904 (2003-02-01), Milka et al.
Anastasiou-Nana, et al., “Relation of Dispersion of QRS and QT in Patients with Advanced Congestive Heart Failure to Cardiac and Sudden Death Mortality”, The American Journal of Cardiology, vol. 85, May 15, 2002, pp. 1212-1217.
Millar, C.K., et al., “Correlation between refractory periods and activation-recovery intervals from electrograms: effects of rate and adrenergic interventions”, Circ. 1985; 72:1372-9.
Haws, C.W., et al., “Correlation between in vivo transmembrane action potential durations and activation-recovery intervals from electrograms. Effects of interventions that alter repolarization time.” Circ. 1990; 81:281-8.
Gepstein, L., et al., “Activation-Repolarization Coupling in the Normal Swine Endocardium,” Cir. 1997; 96:4036-4043.
Chinushi, M., et al., “Cycle Leng-Associated Modulation of the Regional Dispersion of Ventricular Repolarization in a Canine Model of Long QT Syndrome,”Journal of Pacing and Clinical Electrophysiology, vol. 24, No. 8, Aug. 2001, pp. 1247-1257.
Burnes, J.E., et al., “Imaging Dispersion of Myocardial Repolarization, I Comparison of Body-Surface and Epicardial Measures,” Circ. 2001; 104:1299-305.
Ghanem, R.N., et al., “Imaging Dispersion of Myocardial Repolarization, II Noninvasive Reconstruction of Eipcardial Measures,” Circ. 2001; 104:1306-12.
Taggart, P., et al., “Transmural repolarisation in the left ventricle in humans during normoxia and ischaemia,” fromCardiovascular Research, Circ. 201; 50:454-462.
Wantanabe, T., et al., “Regional prolongation of ARI and altered restitution properties cause ventricular arrhythmia in heart failure,” fromAm J Physiol Heart Circ. Physiol., Circ. 2002; 282:H212-218.
Chinushi, M., et al., “Activation-Recovery Interval as a Parameter to Assess the Intracardiac Ventricular Repolarization in Patients with Congenital Long QT Syndrome,” fromThe American Journal of Cardiology, vol. 90, Circ. 2002; 90:432-435.
Laurita, K.R., et al., “Modulation of Ventricular Repolarization by a Premature Stimulus,” Circ. Res. 1996; 79:493-503.
Yu, C., et al., “Tissue Doppler Echocardiographic Evidence of Reverse Remodeling and Improved Synchronicity by Simultaneously Delaying Regional Contraction After Biventricular Pacing Therapy in Heart Failure,” Circ. 2002; 105:438-435.
Bockeman Mark
McDowell Paul H.
Medtronic Inc.
Wolde-Michael Girma
LandOfFree
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