Use of a substance P antagonist for the treatment of skin redden

Details Use of a substance P antagonist for the treatment of skin redden Use of a substance P antagonist for the treatment of skin redden

1995-12-19

1998-04-28

Azpuru, Carlos

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

424443, A61L 1544

Patent

active

057441561

ABSTRACT:
The invention relates to the use of a substance P antagonist for the preparation of a pharmaceutical composition, especially for topical application, for treating skin reddening of neurogenic origin, and especially rosacea and pudic erythema.
The substance P antagonist may be a peptide compound or a nitrogen-containing compound or a nitrogen-containing, sulphur-containing or oxygen-containing heterocyclic compound.

REFERENCES:
patent: 5565462 (1996-10-01), Eitan et al.
British Journal of Pharmacology, vol. 106, No. 2, 1992, pp. 256-262.
European Journal of Pharmacology, vol. 85, 1982, pp. 171-176.
Science (Wash. D.C.), 214 (4524). 1981. 1029-1031.
Ann. Intern. Med., 1981, 95/4 (468-476), USA.
Agents Actions, 1983, 13/2-3 (105-116), Switzerland.
British Journal of Phamacology, vol. 109, No. 1, 1993, pp. 259-264.
British Journal of Pharmacology, Dec. 1993, 119 (4), pp. 1614-1620.
British Journal of Pharmacology, vol. 105, No. 3, 1992, pp. 527-530.

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