Use of a spin trap in a cosmetic or dermatological composition

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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424 59, 424 60, 546184, A61K 31445, A61K 740, A61K 742

Patent

active

055696635

ABSTRACT:
The invention relates to the use of a spin trap employed as an electron paramagnetic resonance measurement probe, in a cosmetic or dermatological composition for the light-protective, anti-ageing and/or anti-acne treatment of the skin. In particular, this spin trap is encapsulated in lipid vesicles which are capable of diffusing into the deep layers of the skin.

REFERENCES:
patent: 4489346 (1989-07-01), Wood et al.
patent: 4863717 (1989-09-01), Keana
patent: 5334756 (1994-08-01), Likibi et al.
patent: 5352442 (1994-10-01), Proctor
International Journal of Pharmaceutics, vol. 62, No. 1, 15 July 1990, Elsevier NL, pp. 75-79, V. Gabrijelcic et al. "Evaluation of liposomes as drug carriers into the skin by one-dimensional EPR imaging" p. 70, col. 2; table 2; p. 79, col. 1, line 23.
Periodicum Biologorum, vol. 93, No. 2, 1991, ZAGREB pp. 245-246, V. Garijelcic et al. "Liposome entrapped molecules penetration into the skin measured by nitroxide reduction kinetic imaging".

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