Use of a salt of an alkaline-earth metal as TNF-A or substance P

Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Heavy metal or compound thereof

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424600, 424617, 424646, 424650, 424677, 424715, 424718, 424722, A61K 3332

Patent

active

058515569

ABSTRACT:
The invention relates to the use of a salt of an alkaline-earth metal in a cosmetic, pharmaceutical, veterinary and/or dermatological composition for treating, in particular, sensitive skins. It relates, in addition, to the use of a salt of an alkaline-earth metal for preventing and/or combating rosacea and/or skin irritation and/or dartre and/or pudic erythema and/or dysesthetic sensation and/or sensation of inflammation and/or pruritus of the skin and/or of the mucous membranes. The salt is in particular strontium nitrate or chloride.

REFERENCES:
patent: 3519711 (1970-07-01), Svigals
patent: 3772431 (1973-11-01), Mlkvy et al.
patent: 3888976 (1975-06-01), Mlkvy et al.
patent: 4477439 (1984-10-01), D'Alelio (deceased)
patent: 4735802 (1988-04-01), Le
patent: 4943432 (1990-07-01), Biener
patent: 4980184 (1990-12-01), Gordon
patent: 4986981 (1991-01-01), Glace et al.
patent: 5047409 (1991-09-01), Di Schiena et al.
patent: 5079010 (1992-01-01), Natterer
patent: 5091171 (1992-02-01), Yu et al.
patent: 5202130 (1993-04-01), Grant et al.
patent: 5296476 (1994-03-01), Henderson
patent: 5593992 (1997-01-01), Adams et al.
Nordia Briefs, "A Salt-Containing Cream for Dry Skin", No. 484, Jan. 1978.
The United States Pharmacopeia, "Alumina/Drug Substances and Dosage Form", pp. 20 and 22 (1975).
Maison G. deNavarre, The Chemistry and Manufacture of Cosmetics, 2nd Ed. vol. IV, p. 1261 (1975).
Alexander A. Fisher, "Irritant Reactions from Topical Urea Preparations Used for Dry Skin Advantages of a Urea-Free `Dead Sea Salt` Cream", Current Contact News, vol. 18, pp. 761-772 (1976).
Rajadhyaksha, Chemical Abstracts, vol. 107, 1987, #223281.
Di Schiena, Chemical Abstracts, vol. 106, 1987, #107768.
Smith et al., Chemical Abstracts, vol. 114, 1991, #206554.
Dufetal et al., Chemical Abstracts, vol. 116, 1992, #135998.
S.M. Moussaoui et al, Br. J. Pharmacol., "A non-peptide NK.sub.1 -receptor antagonist, RP 67580, inhibits neurogenic inflammation postsynaptically", vol. 109, No. 1, 1993, pp. 259-265.
J. Wallengren, Br. J. Dermatol., "Substance P antagonist inhibits immediate and delayed type cutaneous hypersensitivity reactions", vol. 124, No. 4, 1991 pp. 324-328.
J. Wallengren et al, Contact Dermatitis, "Some neuropeptides as modulators of experimental contact allergy", vol. 19, No. 5, 1988, pp. 351-354.
T. Lotti et al., J. Am. Acad. Dermatol., "Treatment of aquagenic pruritus with topical capsaicin cream", vol. 30, No. 2PT1, Feb. 1994, pp. 232-235.
T. Sakurada et al, Brain Res., "A selective and extremely potent antagonist of the neurokinin-1 receptor", vol. 593, No. 2, 1992, pp. 319-322.
K. Folkers et al, Proc. Natl. Acad. Sci. USA, "Spantide II, an effective tachykinin antangonist having high potency", vol. 87, No. 12, 1990, pp. 4833-4855.
Janscro-Gabor, "Action of rare earth metal complexes on neurogenic as well as on bradykinin-induced inflammation", J. Pharm. Pharmac., 22:366-371 (1970).
Dec. 6, 1995; Cosmetologie, Therapeutique, No. 1511, Dec. 17, 19995.
Uy Dong Sohn et al, "Agonist-Independent, Muscle-Type-Specific Signal Transduction Pathways in Cat Esophageal and Lower Esophageal Sphincter Circular Smooth Muscle", J. of Pharmacology & Experimental Therapeutics, 273:481-491 (1995).
Mitsuo Ishizawa, "Contractile Responses of Longitudinal Muscle Strip to 5-HT and Influences of Divalent Cations in the Guinea-Pig Isolated Colon", J. Smooth Muscle Res., 30:65-72 (1994).
H. Goodman, Cosmetic Dermatology, First Edition, Fourth Impression, p. 181 (1936).
Martindale, The Extra Pharmacopoeia, Twenty-seventh Edition, The Pharmaceutical Press, London, pp. 219, 1775 and 1814 (1977).
Sohn et al, Different Receptors Activate a Different Single G-Protein in Esophageal. (Gis) and in LES (Gq) Circular Smooth Muscle, Gastroenterology, vol. 104 (1993).
British Medical Journal (England), vol. 4, Nov. 1975, p. 264.
Chemical Abstracts, vol. 122, No. 16, Apr. 1995, Columbus, Ohio, abstract No. 196540.
Chemical Abstracts, vol. 95, No. 22, Nov. 1981, Columbus, Ohio, abstract No. 192217.
Chemical Abstracts, vol. 120, No. 17, Apr. 1994, Columbus, Ohio, abstract No. 210122.

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