Use of a ribozyme to join nucleic acids and peptides

Details Use of a ribozyme to join nucleic acids and peptides Use of a ribozyme to join nucleic acids and peptides

1999-04-14

2000-11-07

Horlick, Kenneth R.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 912, 530300, 530350, 536 231, 536 241, C12Q 168, C12P 1934, C07H 2104

Patent

active

061435031

ABSTRACT:
Engineered mRNA useful in producing libraries of engineered mRNAs, polypeptide-engineered mRNA conjugates and diverse encoded polypeptide libraries, as well as novel ribozymes that join an mRNA to the translation product of the mRNA and methods of identifying members of diverse encoded polypeptide libraries which exhibit a desired activity. Also described are polypeptide-nucleic acid tag conjugates, methods of producing the conjugates and uses therefor.

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