Use of a prostaglandin in combination with an adrenergic blockin

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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Details

514530, 514573, 514913, A61K 31535, A61K 31215, A61K 3119

Patent

active

049525816

ABSTRACT:
This invention provides a method for treating ocular hypertension or glaucoma in a subject's eye. The method comprises contacting the surface of the eye with an effective intraocular pressure reducing amount of a mixture of an adrenergic blocking agent and a prostaglandin or prostaglandin derivative in an ophthalmically compatible carrier, so as to reduce the intraocular pressure of the eye and maintain such reduced intraocular pressure.
This invention also provides a composition for topical treatment of ocular hypertension or glaucoma in the eye of a subject. The composition comprises an effective intraocular pressure reducing amount of a mixture of an adrenergic block agent and a prostaglandin or prostaglandin derivative in an ophthalmically compatible carrier.

REFERENCES:
patent: 4474751 (1984-10-01), Haslam et al.
patent: 4599353 (1986-07-01), Bito

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