Use of a NK-1 receptor antagonist and an antidepressant and/or a

Details Use of a NK-1 receptor antagonist and an antidepressant and/or a Use of a NK-1 receptor antagonist and an antidepressant and/or a

1997-12-19

2000-09-12

Jarvis, William R. A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

5142362, 514278, 514329, A61K 31675, A61K 31535, A61K 3144, A61K 31445

Patent

active

061178551

ABSTRACT:
The present invention relates to the treatment or prevention of depression and/or anxiety by the administration of a combination of CNS-penetrant NK-1 receptor antagonists and an antidepressant or anti-anxiety agent.

REFERENCES:
patent: 5162339 (1992-11-01), Lowe, III
patent: 5538982 (1996-07-01), Hagan et al.
patent: 5612337 (1997-03-01), Baker et al.
patent: 5716942 (1998-02-01), Dorn et al.
patent: 5719147 (1998-02-01), Dorn et al.
patent: 5728695 (1998-03-01), Harrison et al.
Aguiar, M., et al., Physiology & Behavior, 1996, 60 (4) 1183-1186.
Barden, N., et al., J. Neurochem., 1983, 41, 834-840.
Bristow, L., et al., Eur. J. Pharmacol., 1994, 253, 245-252.
Brodin, E., et al., Neuropharmacology, 1987, 26 (6) 581-590.
Brodin, E., et al., Neuropeptides, 1994, 26, 253-260.
Culman, J., et al., J. Physiol. Pharmacol., 1995, 73, 885-891.
Cutler, et al., J. Psychopharmacol, 1994, 8, A22, 87.
Elliott, P. J., Exp. Brain Res. UK, 1988, 73, 354-356.
F-D-C Reports--Prescription Pharmaceuticals and Biotechnology, Dec. 8, 1997, 59 (49), 10.
File, S. E., Pharm. Biochem. Behavior, 1997, 58, 3, 747-752.
Kramer, et al., Science, 1998, 281, 1640-1645.
Lowe, J., et al., Drug News Perspect, 1992, 5 (4), 223.
Malek-Ahmadi, Neuroscience and Behavioral Reviews, 1992, 16, 365-359.
Rimon, R., et al., Biological Psychiatry, 1984, 19(4), 509-516.
Roccon, et al., Pharmacological Research, 1995, 31, 191.
Rupniak, N., et al., Eur. J. Pharmacol., 1994, 265, 179-183.
Shaikh, M., et al., Brain Research, 1993, 625, 283-294.
Shirayama, Y., et al., Brain Research, 1996, 739, 70-78.
Siegel, R., et al., Neurochem. Int., 1984, 6 (6), 783-789.
Siegel, A., et al., Aggressive Behavior, 1995, 21, 49-62.
Teixeira, R., et al., European J. Pharm., 1996, 311, 7-14.
Vassout, et al., Neuropeptides, 1994, 26 (Suppl. 1), 38.
Wahlestedt, Science, 1998, 281, 1624-1625.
Wall Street Journal, Aug. 13, 1998, B1, Col. 2.

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