Use of a mixture of sodium hyaluronate and chondroitin...

Details Use of a mixture of sodium hyaluronate and chondroitin... Use of a mixture of sodium hyaluronate and chondroitin...

2005-09-27

2005-09-27

Wilson, James O. (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

Reexamination Certificate

active

06949525

ABSTRACT:
This invention is related to the use of the composition formed by sodium hyaluronate and sodium chondroitin sulfate for the treatment of chondral lesions in osteoarthritis, and to the use of such composition in the manufacture of a product for such treatment.

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Buckwalter et al., “The Increasing Need for Nonoperative Treatment of Patients with Osteoarthritis,”Clinical Orthopaedics and Related Research, 385:36-45 (2001).
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Nerucci et al., “Effects of chondroitin sulfate and interleukin-1β on human chondrocyte cultures exposed to pressurization: a biochemical and morphological study,”Osteoarthritis and Cartilage8:279-287 (2000).
Watanabe et al., “Roles of Aggrecan, a Large Chondroitin Sulfate Proteoglycan, in Cartilage Structure and Function,”J. Biochem124:687-693 (1998).

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