Use of a cytokine regulatory agent to treat rheumatoid arthritis

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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514 16, 514 17, 514 18, 530317, 530322, 530328, 530329, 530330, A61K 3800, C07K 500, C07K 700, C07K 1700

Patent

active

057417741

ABSTRACT:
The present invention relates to the use of a cytokine regulatory agent to reduce the severity of rheumatoid arthritis.

REFERENCES:
patent: 5420109 (1995-05-01), Suto et al.
patent: 5457129 (1995-10-01), Aggarwal et al.
Arai et al. Cytokines:Coordinators of immune and inflammatory responses. Annu. Rev. Biochem. 59: 783-836 Jun. 1990.
Wooley et al., "Influence of a Recombinant Human Soluble Tumor Necrosis Factor Receptor FC Fusion Protein on Type II Collagen-Induced Arthritis in Mice," J. Immunol. 151:6602-6607 (1993).
Wooley et al., "The Effect of an Interleukin-1 Receptor Antagonist Protein on Type II Collagen-induced Arthritis and Antigen-induced Arthritis in Mice," Arthr. Rheum. 36:1305-1314 (1993).

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