Use of a baculovirus to express and exogenous gene in a mammalia

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for...

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4353201, 435325, 536 232, C12N 900, C12N 1563, C12N 510, C07H 2104

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058719865

ABSTRACT:
Disclosed is a method of expressing an exogenous gene in a mammalian cell, involving infecting the cell with a baculovirus whose genome carries an exogenous gene, and growing the cell under conditions such that the gene is expressed. Also disclosed is a method of treating a gene deficiency disorder in a mammal by providing to a cell a therapeutically effective amount of a baculovirus whose genome carries an exogenous gene and growing the cell under conditions such that the exogenous gene is expressed in the mammal.

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