Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-07-21
1990-05-08
Robinson, Allen J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514262, A61K 31505
Patent
active
049238744
ABSTRACT:
A class of 8-azapurin-6-one derivatives is described for use in control of hypertension. A compound of particular interest is 8-aza-2-(2-n-propoxyphenyl)purin-6-one.
REFERENCES:
patent: 3819631 (1974-06-01), Broughton et al.
W. R. Kukovetz et al, Nauyn-Schmiedeberg's Arch. Pharmacol., 310, 129-138 (1979).
W. Martin et al, J.P.E.T., 237(2), 539-547 (1986).
W. Martin et al., Br. J. Pharm., 89, 557-561 (1986).
R. W. Lappe et al., Circ. Res., 56, 606-612 (1985).
R. F. G. Booth et al., Biochem. Pharm. 36(20), 3517-3521 (1987).
N. Frossard et al, Br. J. Pharm., 73, 933-938 (1981).
R. M. Rudd, Br. J. Dis. Chest., 77, 78-86 (1983).
J. E. McCormick et al, Proc. R. Ir. Acad., Sect. B, 83, B(1-16), 125-138 (1983).
Manning Robert E.
McMahon Ellen G.
G. D. Searle & Co.
Keane J. Timothy
Matukaitis Paul D.
Robinson Allen J.
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