Use of 6-amino-9-(substituted benzyl)purines and their correspon

Details Use of 6-amino-9-(substituted benzyl)purines and their correspon Use of 6-amino-9-(substituted benzyl)purines and their correspon

1974-08-09

1976-04-27

Rosen, Sam

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

260252, A61K 3152

Patent

active

039535975

ABSTRACT:
Novel 6-amino-9-(substituted benzyl)purines are prepared by allowing an appropriate substituted benzyl halide, e.g., a substituted benzyl chloride, to react with adenine under the appropriate conditions. Oxidation of the resulting purine derivatives yields the corresponding N.sup.1 -oxides. These compounds, i.e., both the purine derivatives and the N.sup.1 -oxides thereof, have anti-coccidial activity and are useful for controlling cecal and/or intestinal coccidiosis when administered in minor quantities to animals, in particular to poultry, usually in admixture with animal sustenance.

REFERENCES:
schaeffer et al., -- J. of Med. Chem. Vol. 13, (1970), pp. 452-455.

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