Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1989-06-23
1991-06-11
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549484, 549487, 544152, 544379, 546214, C07D30752, C07D30754, A61K 3134
Patent
active
050232720
ABSTRACT:
A method of preventing epileptic seizures in a human or mammal subject susceptible to said seizures, comprising systemically administering to said subject a safe and effective amount of a compound of the formula: ##STR1## wherein (a) X is halo or hydrogen, and Y is a substituent selected from the group consisting of unsubstituted or halogen-substituted methyl, halo, nitro, amino, and methoxy; and
REFERENCES:
patent: 3856825 (1974-12-01), Wright et al.
patent: 4035394 (1977-07-01), Pelosi, Jr. et al.
patent: 4128550 (1978-12-01), Pelosi, Jr. et al.
patent: 4162257 (1979-07-01), Pelosi, Jr. et al.
patent: 4403097 (1983-09-01), Pelosi, Jr. et al.
patent: 4643996 (1987-02-01), Pelosi, Jr. et al.
Oleinik, A. E. et al., "Synthesis and Tuberculostatic Activity of 5-Arylpyromucic Acid Derivatives", Pharmaceutical Chemical Journal, vol. 10, No. 4, (Apr. 1976), pp. 463-465.
Burch, H., R. White, G. Wright & M. Goldenberg, "Phenyl Furans IV: Spasmolytic 3-Diethylamino-2,2-(Dimethyl)Propyl Esters of 5-Substituted Phenyl-2-Furancarboxylic Acids", Journal of Pharmaceutical Sciences, vol. 69, No. 1, (Jan. 1980), pp. 107-110.
Goldenberg, M., "F-461, 3-Diethylamino-2,2-Dimethylpropyl 5-(P-Nitrophenyl)-2-Furoate Hydrochloride, a New Non-Anticholinergic Spasmolytic and a Gastric Acid Inhibitor", Arch. Int. Pharmacodyn, vol. 222, pp. 27-39 (1976).
Burch Homer A.
Castellion Alan W.
Pelosi, Jr. Stanford S.
Clark Karen F.
Datlow Philip I.
Norwich Eaton Pharmaceuticals, Inc.
Schaeffer Jack D.
Shah Mukund J.
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