Use of 3'-deoxythymidin-2'-ene (3'deoxy-2',3'-didehydrothymidine

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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514934, A61K 3170

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active

049786555

ABSTRACT:
This invention relates to the use of 3'-deoxythymidin-2'-ene (3'deoxy-2',3'-didehydrothymidine) in treating patients infected with a retrovirus.

REFERENCES:
patent: 3322747 (1967-05-01), Shen et al.
patent: 3817982 (1974-06-01), Verheyden et al.
patent: 4360522 (1982-11-01), Shaeffer et al.
patent: 4710492 (1987-12-01), Lin et al.
Mitsuya et al., Proc. Natl. Acad. Sci. USA, 82 pp. 7096-7100 (1985).
Mitsuya et al., Proc. Natl. Acad. Sci. USA, 83 pp. 1911-1915 (1986).
Fischl et al., The New England J. of Medicine, 317 No. 4, pp. 185-191 (1987).
Herdewijn et al., J. Med. Chem., 30 pp. 1270-1278 (1987).
Lin et al., Biochemical Pharmacolog, vol. 36, No. 17, pp. 2713-2718 (1987).
Lin et al., J. Med. Chem., 30 pp. 440-444 (1987).
Kim et al., J. Med. Chem., 30 862-866 (1987).
Lin et al., Biochemical Pharmacology, 36, No. 3, 311-316 (1987).
DeClercq, J. Antimicrobial Agents and Chemotherapy 14, Suppl. A, 85-95 (1984).
De Clercq et al., Biochemical Pharmacology, 29, 1849-1851 (1980).
Machida, Antimicrobial Agents and Chemotherapy, 29, No. 3, 524-526 (1986).
De Clercq, et al., J. Med. Chem., 29 213-217 (1986).
Robins, "Synthetic Antiviral Agents", (4 EN, Jan. 27, 1986.
D. Dormant, B. Spire, F. Barre-Sinoussi, L. Montagnier and J. C. Chermann, Ann. Inst. Pasteur/Virol., 75, 136E, (1985).
W. Rosenbaum, D. Dormont, B. Spire, E. Vilmer, M. Gentilini, C. Griscelli, L. Montagnier, F. Barre-Sinoussi and J. C. Chermann, Lancet, i, 450, (1985).
D. D. Ho, K. L. Hartshorn, T. R. Rota, C. A. Andrews, J. C. Kaplan, R. T. Schoolkey and M. S. Hirsch, Lancet, i, 602 (1985).
J. B. McCormick, J. P. Getchell, S. W. Mitchell and D. R. Hicks, Lancet, ii, 1367, (1984).
E. G. Sandstrom, J. C. Kaplan, R. E. Byington and M. S. Hirsch, Lancet, i, 1480, (1984).
P. S. Sarin, Y. Taguchi, D. Sun, A. Thornton, R. C. Gallo and B. Oberg, Biochem. Pharmac., 34, 4075, (1985).
R. Anand, J. L. Moore, A. Srinivason, V. Kalyanaraman, D. Francis, P. Feorino and J. Curran, Abstracts of the International Conference on Acquired Immune Deficiency Syndrome (AIDS), Apr. 14-17, Atlanta, Ga. p. 72, (1985).
H. Mitsuya, M. Popovic, R. Yarchoan, S. Matsushita, R. C. Gallo and S. Broder, Science, 226, 172, (1984).
H. Mitsuya, S. Matsushita, M. E. Harper and S. Broder, Cancer Res., 45, 4583s, (1985).
E. DeClercq, Cancer Lett. 8, 9 (1979).
A. Pompidou, D. Zagury, R. C. Gallo, D. Sun, A. Thornton and P. S. Sarin, Lancet, ii, 1423, (1985).
P. Chandra and P. S. Sarin, Drug Res., 36 184, (1986).
R. Anand, J. Moore, P. Feorino, J. Curran and A. Srinivasan, Lancet, i, 97, (1986).
P. S. Sarin, R. C. Gallo, D. I. Scheer, F. Crews and A. S. Lippa, New Engl. J. Med., 313, 1289, (1985).
W. Ostertag, T. Cole, T. Crozier, G. Gaedicke, J. Kind, N. Kluge, J. C. Krieg, G. Roselser, G. Sheinheider, B. J. Weimann and S. K. Dube, Proceedings of the 4th International Symposium of the Princess Takamatsu Cancer Research Fund, Tokyo, 1973, Differentiation and Control of Malignancy of Tumor Cells, Eds. W. Nakhara, T. Ono, T. Sugimura and H. Sugano, p. 485, University of Tokyo Press, Tokyo, (1974).
W. Ostertag, C. Roseler, C. J. Kreig, T. Cole, T. Crozier, G. Gaedicke, G. Steinheider, N. Kluge and S. K. Dube, Proc. Natn. Acad. Sci. USA, 71, 4980, (1974).
S. L. Dube, G. Gaedicke, N. Kluge, B. J. Weimann, H. Melderis, G. Steinheider, T. Crozier, H. Beckmann and W. Ostertag, Proceedings of the 4th International Symposium of the Princess Takamatsu Cancer Research Fund, Tokyo, 1973, Differentiation and Control of Malignancy

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