Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1981-12-15
1986-02-25
Schwartz, Richard A.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514313, 514314, 514333, 514341, 548379, A61K 31415, A61K 3144, A61K 3147, C07D23106
Patent
active
045729131
ABSTRACT:
Compounds of formula (I) ##STR1## inhibit both the cyclo-oxygenase and lipoxygenase pathways of arachidonic acid oxygenation and are useful in medicine as, e.g., anti-inflammatory and anti-asthmatic agents.
The compounds may be administered as the raw chemical or in association with a carrier as a pharmaceutical formulation.
The compounds may be prepared by methods analogous to those known in the art, e.g., by the method of Duffin and Kendall in J. Chem. Soc. (1954), 408-415, or by other methods.
REFERENCES:
Duffin et al., J. Chem. Soc. 1954, pp. 408-415.
Kost et al., Fhur. Obshchei Khim. 29, pp. 498-502 (1959), [Translation and Abstract].
Caldwell Albert G.
Collard David
Copp Frederick C.
Briscoe Kurt G.
Brown Donald
Burroughs Wellcome Co.
Schwartz Richard A.
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