Use of 3,4-diphenyl chromans for the manufacture of a pharmaceut

Details Use of 3,4-diphenyl chromans for the manufacture of a pharmaceut Use of 3,4-diphenyl chromans for the manufacture of a pharmaceut

1997-08-18

1999-03-23

Henley, III, Raymond

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514456, A61K 3140, A61K 3135

Patent

active

058860215

ABSTRACT:
The present invention provides novel uses of compounds of general formula I ##STR1## wherein R.sup.1, R.sup.4 and R.sup.5 are individually hydrogen, hydroxy, halogen, trifluoromethyl, lower alkyl, lower alkoxy or (tertiary amino)(lower alkoxy); and R.sup.2 and R.sup.3 are individually hydrogen or lower alkyl, or as a pharmaceutically acceptable salt thereof in combination with a pharmaceutically acceptable carrier for the manufacture of a pharmaceutical composition for vasodilatory treatment or prophylaxis.

REFERENCES:
patent: 3340276 (1967-09-01), Carney et al.
patent: 3822287 (1974-07-01), Bolger
patent: 4447622 (1984-05-01), Salman et al.
patent: 5280040 (1994-01-01), Labroo et al.
Chak et al., "Acute Toxicity & Pharmacology of Centchroman", Indian Journal of Experimental Biology, vol. 15, Dec. 1977, pp. 1159-1161.
Ray et al., "An X-ray Crystallographic Study of the Nonsterodial Contraceptive Agent Centchroman", J. Med. Chem. Soc., vol. 37, pp. 696-700(1984).
Dhawan et al., Anti-inflammatory And Some Other Pharmacological Effects of .beta.-pyrrolidinoethoxy)-phenyl!-7-methoxy-chroman (Centchroman), Br. Pharmac. (1973), vol. 49, pp. 64-73.
Grant et al., Grant & Hackh's Chemical Dictionary, Fifth Edition, McGraw-Hill Book Company(1985).

Affiliated with

Also associated with

Rating

Use of 3,4-diphenyl chromans for the manufacture of a pharmaceut does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of 3,4-diphenyl chromans for the manufacture of a pharmaceut, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of 3,4-diphenyl chromans for the manufacture of a pharmaceut will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2125759