Use of 3,4-diphenyl chromans for the manufacture of a pharmaceut

Details Use of 3,4-diphenyl chromans for the manufacture of a pharmaceut Use of 3,4-diphenyl chromans for the manufacture of a pharmaceut

1997-01-10

1998-10-27

Criares, Theodore J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514456, A61K 3140, A61K 3135

Patent

active

058278737

ABSTRACT:
The present invention provides novel uses of compounds of general formula I ##STR1## wherein R.sup.1, R.sup.4 and R.sup.5 are individually hydrogen, hydroxy, halogen, trifluoromethyl, lower alkyl, lower alkoxy or (tertiary amino)(lower alkoxy); and R.sup.2 and R.sup.3 are individually hydrogen or lower alkyl, or as a pharmaceutically acceptable salt thereof in combination with a pharmaceutically acceptable carrier for the manufacture of a pharmaceutical composition for the treatment or prophylaxis of cerebral degenerative disorders.

REFERENCES:
patent: 4447622 (1984-05-01), Salman et al.
patent: 5554601 (1996-09-01), Simpkins et al.
Ray et al., "An X-ray Crystallographic Study of the Nonsterodial Contraceptive Agent Centchroman", J. Med. Chem. Soc., vol. 37, pp. 696-700. (1994).

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