Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1994-09-30
1996-12-31
Fay, Zohreh
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514277, 514369, 514438, 514461, A61K 3170, A61K 31435, A61K 31425, A61K 3138
Patent
active
055894640
ABSTRACT:
Compounds of the formula: ##STR1## are useful for treatment of cataracts in mammals.
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Garner, W. H., et. al., "Mechanism of Delay of Galactosemic Cataract with Oxothiazolidine Carboxylic Acid (OTC)," Tuesday AM: Lens Poster Presentation, p. 147. May 1, 1988.
Nagasawa, H. T., et. al., "2-Substituted Thiazolidine-R(R)-carboxylic Acids as Prodrugs of L-Cysteine. Protection of Mice against Acetaminophen Heptatoxicity," J. Med. Chem,, 1984, 27, 591-596.
Holleschan, A. M., et. al., "Procedures for Augmenting Glutathione in Cultured Rabbit Lenses," Lens Research, 3(1-2), 1097-118, 1986.
Roberts, T. C., et. al., "Prodrugs of L-Cysteine as Protective Agents against Acetaminophen-Induced Heptatoxicity. 2-(Polyhydroxyalkyl)-and 2-(Polyacetoxylalkyl)thiazolidine-4(R)-carboxylic Acids," J. Med. Chem, 1987, 30, 1891-1896.
Garner William H.
Wheeler Larry A.
Allergan
Baran Robert J.
Fay Zohreh
Lambert Howard R.
Voet Martin A.
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