Use of 2-(phenoxypropanolamino) ethoxphenoxy-acetic acid and its

Details Use of 2-(phenoxypropanolamino) ethoxphenoxy-acetic acid and its Use of 2-(phenoxypropanolamino) ethoxphenoxy-acetic acid and its

1991-07-30

1993-09-14

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

A61K 31165

Patent

active

052449238

ABSTRACT:
The use of a compound of the formula (I): ##STR1## wherein R is hydroxy or 2-methoxyethylamino or a pharmaceutically acceptable salt thereof, in stimulating the `atypical` .beta.-adrenoceptors in the gastrointestinal tract and thereby inhibiting gastrointestinal motility. These compounds may be used for treating medical conditions wherein inhibition of gastrointestinal motility is thought to be of value, such as in the treatment of inflammatory bowel disease, irritable bowel syndrome (IBS), non specific diarrhoea and dumping syndrome.

REFERENCES:
patent: 4772631 (1988-09-01), Holloway
patent: 4927836 (1990-05-01), Holloway
patent: 4977148 (1990-12-01), Holloway
patent: 5002946 (1991-03-01), Manara et al.
Manara et al., Trends Pharmacol. Sci., pp. 229-230 (1990).

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