Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-03-29
2005-03-29
Morris, Patricia L. (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S199000
Reexamination Certificate
active
06872740
ABSTRACT:
The present invention relates to the use of 2-amino-4-heteroarylethyl-thiazoline derivatives of formula (I)in which Het represents a thienyl, pyrimidyl, pyridyl or thiazolyl radical or pharmaceutically acceptable salts thereof as inhibitors of inducible NO-synthase.
REFERENCES:
patent: WO 9412165 (1994-06-01), None
patent: WO 9511231 (1995-04-01), None
patent: WO 9614842 (1996-05-01), None
Creeke Paul et al, Synthesis and Elaboration of Heterocycles Via Iodocyclisation of Unsaturated Thioureas, Tetrahedron, (1989, pp. 4435-4438, vol. 30, No. 33).
Mark Sabat et al., Synthesis of Unnatural Amino Acids via Suzuki Cross-Coupling of Enantiopure Vinyloxazolidine Derivatives, Organic Letters (2000, pp. 1089-1092, vol. 8, No. 8).
Yoshiya Noike, Syntheses of quinolizine derivatives. VI. Syntheses of 30aminoquinolizines. 1. Syntheses of Heterocyclic Compounds (1960, pp. 11021 b).
Bacque Eric
Bigot Antony
Carry Jean-Christophe
Mignani Serge
Aventis Pharma S.A.
Bolcsak James W.
Morris Patricia L.
Newman Irving
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