Use of 2,3-dimethoxy-5-methyl-6-decaprenyl-1,4-benzoquinone

Details Use of 2,3-dimethoxy-5-methyl-6-decaprenyl-1,4-benzoquinone Use of 2,3-dimethoxy-5-methyl-6-decaprenyl-1,4-benzoquinone

1999-10-12

2001-05-08

Criares, Theodore J. (Department: 1617)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ketone doai

C424S557000

Reexamination Certificate

active

06228891

ABSTRACT:

2,3-Dimethoxy-5-methyl-6-decaprenyl-1,4-benzoquinone is also known by the designation of coenzyme Q10. This substance plays a role in the respiratory chain and, in addition, is an anti-oxidant which is capable of scavenging free radicals, which are transmitted by vitamins, in particular. In addition, Q10 determines the elasticity and dynamics of cell membranes. Therefore, it is recommended as a monopreparation and in combination with other active substances for oral administration. For skin care, it is additionally offered in the form of a liposome cream which allows the active ingredient to penetrate through the horny layer barrier and then to accumulate in the various strata of the skin. The liposome cream used to date has been prepared on the basis of lecithins, forming a lipid bilayer around an aqueous interior space. Q10 deposits inside the membrane.


REFERENCES:
patent: 4654373 (1987-03-01), Bertelli
patent: 4824669 (1989-04-01), Folkers et al.
patent: 5451569 (1995-09-01), Wong et al.
patent: 5912272 (1999-06-01), Hoppe et al.
patent: 2184355A (1987-06-01), None
patent: 63-036789 (1988-02-01), None
Reynolds,Martindale The Extra PharmacopoeiaThirty-First Edition, p. 1764: Ubidecarenone (1996).

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