Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-01-11
1999-12-28
Moezie, M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514456, 514909, 514910, A61K 3140
Patent
active
060082429
ABSTRACT:
The present invention provides novel uses of compounds of general formula I ##STR1## wherein R.sup.1, R.sup.4 and R.sup.5 are individually hydrogen, hydroxy, halogen, trifluoromethyl, lower alkyl, lower alkoxy or (tertiary amino)(lower alkoxy); and R.sup.2 and R.sup.3 are individually hydrogen or lower alkyl, or as a pharmaceutically acceptable salt thereof in combination with a pharmaceutically acceptable carrier for the manufacture of a pharmaceutical composition for the treatment or-prophylaxis of obesity.
REFERENCES:
patent: 3822287 (1974-07-01), Bolger
patent: 4447622 (1984-05-01), Salman et al.
patent: 5280040 (1994-01-01), Labroo et al.
Chak et al., "Acute Toxicity & Pharmacology of Centchroman", Indian Journal of Experimental Biology, vol. 15, Dec. 1977, pp. 1159-1161.
Ray et al., "An X-ray Crystallographic Study of the Nonsterodial Contraceptive Agent Centchroman", J. Med. Chem. Soc., vol. 37, pp. 696-700, 1994.
Bain Steven
Guldhammer Birgitte Hjort
Korsgaard Niels
Shalmi Michael
Agus Cheryl H.
Moezie M.
Novo Nordisk A S
Zelson Steve T.
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