Use of 1,4-dihydropyridines in diabetes

Details Use of 1,4-dihydropyridines in diabetes Use of 1,4-dihydropyridines in diabetes

1993-07-09

1995-08-01

O'Sullivan, Peter

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

544356, 544866, C07D21122

Patent

active

054381444

ABSTRACT:
The invention relates to the use of 1,4-dihydropyridines having calcium antagonistic action, in particular of nimodipine, for the preparation of medicaments for controlling damage to peripheral nerves which is caused by diabetes.

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E. Sporel-Ozakat et la., "Nimodipine and Central Nervous System Function: New Vistas", Schattauer Verlag Stuttgart, 71-85 (1989).
R. E. Sporel-O zakat, Dissertation, "Peripheral Nerve Damage and Repair: A Pharmacological Therapeutical Approach", University of Utrecht, 1990, pp. 93-98.
A. K. Sharma et al., "Animal Models: Pathology and Pathophysiology", Diabetic neruopathy (1987), pp. 237-252.
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A. C. Kappelle et al., "The Ca-antagonist nimodipine counteracts the onset . . . ", Neuroscience Research Communications, vol. 10, No. 2, 1992, pp. 95-104.
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