Use in an animal host and precursors for vaccines utilizing avia

Details Use in an animal host and precursors for vaccines utilizing avia Use in an animal host and precursors for vaccines utilizing avia

1983-12-20

1985-11-12

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Lymphokine

A61K 39145

Patent

active

045527571

ABSTRACT:
A method of producing a vaccine useful in animals which comprises producing a reassortment by gene exchange from an avian influenza A virus parent and an animal influenza A virus parent and then selecting for the reassortant containing two animal surface antigen genes and six avian internal genes by temperature and antibodies.

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Murphy et al., Infection and Immunity, 37:1119-1126, Sep. 1982.
Murphy et al., Science, 218:1330-1332, Dec. 24, 1982.
Hinshaw et al., C.A. 99, #118900r, (1983), Virology, 1983, 128(1):260-3, Altered Tissue Tropism of Human-Avian Reassortant Influenza Viruses.
Kim et al., C.A. 87, #148423q, (1977) Izv. Akad. Naukkaz. Ssr. Ser. Biol., 1977, 15(4):29-35, Effect of Physicochemical Factors on the Enzymic Activity of Influenza Virus from Man and Birds and Their Recombinants.
Podchernyaeva, C.A. 92 #211654d, (1980).

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