Uromodulin and a process of purifying it

Details Uromodulin and a process of purifying it Uromodulin and a process of purifying it

1986-12-19

1990-12-11

Draper, Garnette D.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

530351, 530395, 530412, 530413, 530417, 530834, 514 2, 514 8, 514 12, 514 21, 514886, 514885, 424 851, 424 852, C07K 1506, C07K 328

Patent

active

049772449

ABSTRACT:
This invention relates to processes for producing uromodulin, a glycoprotein having a molecular weight of 85 kilo daltons. This glycoprotein, which is isolated from crude urine, as well as its carbohydrate derivatives, are useful as immunosuppressive agents or anti-inflammatory agents.

REFERENCES:
patent: 4661447 (1987-04-01), Fabricius et al.
patent: 4681844 (1987-07-01), Fabricius et al.
Walsh, CA vol. 107, 1987, #37792p.
Roberts et al., J. Exp. Med. 163, 1986, pp. 511-119.

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