Urogenital sinus derived growth inhibitory factor

Details Urogenital sinus derived growth inhibitory factor Urogenital sinus derived growth inhibitory factor

1988-09-02

1993-03-23

Moezie, F. T.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

530324, 530339, 530828, 514 2, 514 21, C07K 1500, C12N 500

Patent

active

051963345

ABSTRACT:
A process is provided for purifying Urogenital Sinus Derived Growth Inhibitory Factor (UGIF) from embryonic tissue which comprises chromatographing medium from cultures of embryonic tissue derived from the urogenital sinus by gel filtration chromotography. Further purification by reverse phase high pressure liquid chromotography is also demonstrated. The UGIF is obtained in 70-fold to 8000-fold purification over the conditioned medium. A UGIF composition of matter is also provided.

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