Urine soluble tumor necrosis factor receptor for diagnosis of de

Details Urine soluble tumor necrosis factor receptor for diagnosis of de Urine soluble tumor necrosis factor receptor for diagnosis of de

1998-08-18

2000-01-25

Minnifield, Nita

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 71, 435 691, 435 697, 435 696, 4241331, 4241451, G01N 3353, C12P 2106, C12P 21021, A61K 39395

Patent

active

060177187

ABSTRACT:
A method for predicting the presence of deep venous thrombosis in a patient comprises measuring the concentration of soluble tumor necrosis factor receptor-1 (p55) in the patient's urine and comparing the measured concentration to an established baseline concentration. A concentration in the patient's urine greater than the established baseline concentration is predictive of the presence of deep venous thrombosis.

REFERENCES:
S. Taheri et al., (Angiology--The Journal of Vascular Diseases, vol. 49, No. 7, 1998) Diagnosis of Deep Venous Thrombosis by Use of Soluble Necrosis Factor Receptor.
Seckinger et al , A human inhibitor of tumor necrosis factor alpha, J.Exp.Med, vol., 157, pp. 1511-1516, 1988.
Zangerle et al , Tumor necrosis factor alpha and soluble tumor necrosis factor receptors in individuals with human immunodeficiency virus infection, Immunology letters, vol., 41, pp. 229-234, 1994.

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