Textiles: fiber preparation
Patent
1975-02-11
1976-06-01
Naff, David M.
Textiles: fiber preparation
195 66B, 195 68, 195 99, 424 2, G01N 3114
Patent
active
039606694
ABSTRACT:
A test for maladies which cause deviations in the rate of production of fibrinolytic enzymes is carried out by adding controlled quantities of standardized thrombin and fibrinogen solutions to a urine specimen and noting the clotting time. Shortening of the clotting time from that measured with urine from healthy subjects indicates that the quantity of fibrin degradation products (FDP) in the blood is below normal. Increased production of such FDP may be due to the presence of a blood clot, an embolism, severe liver disturbance, cancer, extensive myocardial infarction, or pancreatic inflammatory disease. Conversely, decreased production of said FDP is taken as indicating a condition presaging the formation of a blood clot, or a significant decrease in the rate of production of fibrinolytic enzymes. The detection of either type of deviation can be used as the basis for diagnosis and treatment.
REFERENCES:
patent: 3853710 (1974-12-01), Innerfield
Matsushama et al., Simplified Method for Detecting Fibrinogen and its Derivatives by Tanned Red Blood Hemagglutination Inhibition Immune Assay. Chem. Abst., Vol. 72, 87898g 1970 (p. 159).
Flute, P. T. The Assessment of Fibrinolytic Activity in Blood, Brit. Med. Bull. vol. 20, No. 3, 1964 (pp. 195-199).
Association for Pharmacologic Research, Inc.
Naff David M.
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