Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Synthesis of peptides
Patent
1988-03-11
1990-08-07
Moskowitz, Margaret
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Synthesis of peptides
530334, 530337, 530333, 548227, 548183, 544 97, 544 54, 540488, C07K 100, C07D27700, C07D27900, C07D28100, C07D26300, C07D26500, C07D26700
Patent
active
049469428
ABSTRACT:
The invention relates to urethane-protected amino acid-N-carboxyanhydride and N-thiocarboxyanhydride compounds which are useful in peptide, polypeptide and protein synthesis. Disclosed herein is the preparation and use of these novel compounds.
REFERENCES:
patent: 4038282 (1977-07-01), Hirschmann et al.
patent: 4267344 (1981-05-01), Halstrom et al.
Akiyama, M., Tetrahedron Letters, 28: 2599-2600, 1979.
Shimizu, K., Bull. Chem. Soc. Jpn., 57: 495-499, 1984.
Hirschmann, R., JACS, 93 (11): 2746-2754, 1971.
Halstrom, J., Peptides (Eur. Peptide Symp., 12th, 1972), 1973.
Bodanszhy, M., Principles of Peptide Synthesis, Springer-Verlag, N.Y.: 25-86, 1984.
Blacklock, T. J., The Peptides, 9: 39-102, 1987.
Kricheldorf, Makromol. Chem., 178: 905-939, 1977.
Cohen Michael P.
Fuller William D.
Goodman Murray
Naider Fred R.
BioResearch, Inc.
Moskowitz Margaret
Perkins Susan M.
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