Ureidoalkanoylaminocarbonyl amino and imino acids and esters

Details Ureidoalkanoylaminocarbonyl amino and imino acids and esters Ureidoalkanoylaminocarbonyl amino and imino acids and esters

1987-12-28

1989-03-07

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546206, 546207, 546208, 546209, 546210, 548300, 548517, 548518, 548525, 548527, 548532, 548533, 548534, 548535, C07D25118, C07D40900

Patent

active

048107913

ABSTRACT:
Compounds of the formula ##STR1## are disclosed. These compounds are useful as hypotensive agents due to their angiotensin converting enzyme inhibition activity and depending upon the definintion of X may also be useful as analgesics due to their enkephalinase inhibition activity.

REFERENCES:
patent: 4329473 (1982-03-01), Almquist et al.
patent: 4621092 (1986-11-01), Natarajan et al.
patent: 4623729 (1986-11-01), Natarajan et al.
Meyer et al., "Novel Synthesis of . . . ", J. Med. Chem., 1981, vol. 24, pp. 964-969.
Almquist et al., "Derivatives of Potent Angiotensin Converting Enzyme Inhibitor . . . ", J. Med. Chem., 1982, vol. 25, 1292-1299.

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