Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2010-03-03
2011-12-06
Chandrakumar, Nizal (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S483000, C514S616000
Reexamination Certificate
active
08071640
ABSTRACT:
A method for treating a cytotoxic disease by administrating compounds having a general formula X-(A)n-Y, wherein: n varies between 6 and 20; X denotes a hydrogen atom, an RaCO, RaOCO, RaNHCO or RaSO2 group, Ra being an alkyl, alkenyl, alkynyl, aryl, aralkyl, heteroaryl group, the groups being substituted or not, on condition that X is different from H when n is equal to 6; A denotes either a group having formula (I) or (II), wherein Ri is a hydrogen atom, an amino acid side chain, an alkyl, alkenyl, alkynyl, aryl, aralkyl or heteroaryl group, said groups being substituted or not, i being an integer of between 1 and n; Y is an NRbRc, Rb and Rc group having the same meaning as given earlier for Ra.
REFERENCES:
patent: 254 319 (1988-02-01), None
patent: 00/42009 (2000-07-01), None
Freshney, Culture of Animal Cells, A Manual of Basic Technique, Alan R. Liss, Inc., 1983, New York, p. 4.
Tamilarasu et al., “Targeting RNA with peptidomimetic oligomers in human cells” Bioorganic & Medicinal Chemistry Letters, Oxford, GB, vol. 11, No. 4, Feb. 26, 2001, pp. 505-507, XP004230046 ISSN: 0960-894X p. 506; figure 1C.
Guichard et al (Tetrahedron Letters 41 (2000) 1553-1537).
Tamilarasu (Journal of American Chemical Society, 1999, 121(7), 1597-1598).
Wang et al. (Journal of American Chemical Society, 1997, 119(7),6444-6445).
Briand Jean-Paul
Guichard Gilles Francois Roger
Neuberg Patrick
Semetey Vincent
Centre National de la Recherche Scientifique
Chandrakumar Nizal
Young & Thompson
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