Urea derivatives as integrin α4 antagonists

Details Urea derivatives as integrin α4 antagonists Urea derivatives as integrin α4 antagonists

2007-08-07

2007-08-07

McKenzie, Thomas (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S300000, C544S391000, C546S335000, C546S234000, C546S226000, C546S236000, C546S294000, C560S034000

Reexamination Certificate

active

10466665

ABSTRACT:
Novel antagonists of ∝4β1 integrin and/or ∝4β7 integrin of the general Formula I: wherein R1, R2, R5, L1, L2, Rb, W and Z are as defined in any one of claims1to13,A represents —CH— or a nitrogen atom, and p is from 0 to 4.

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