Urea derivatives as inhibitors for CCR-3 receptor

Details Urea derivatives as inhibitors for CCR-3 receptor Urea derivatives as inhibitors for CCR-3 receptor

2005-04-05

2005-04-05

Seaman, D. Margaret (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

C560S034000, C560S169000, C562S435000, C562S027000, C562S028000, C562S050000, C562S052000, C562S056000, C546S175000, C546S334000, C548S253000, C548S335500, C548S504000, C548S566000, C549S434000, C549S077000, C549S484000

Reexamination Certificate

active

06875884

ABSTRACT:
Urea and thiourea derivatives inhibit cell function of the chemokine receptor CCR-3. These compounds offer an effective means for treating a range of diseases thought to be mediated by the CCR-3 receptor. A variety of useful urea and thiourea derivatives can be synthesized using liquid and solid phase synthesis protocols.

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