Urea compounds, compositions and methods of use and preparation

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S423000, C548S139000, C548S195000, C548S518000, C548S519000, C548S527000, C548S538000

Reexamination Certificate

active

06852752

ABSTRACT:
Novel hydroxamic acid compounds are disclosed. These hydroxamates inhibit peptide deformylase (PDF), an enzyme present in prokaryotes and are therefore useful as antimicrobials and antibiotics. Methods of synthesis and of use of the compounds are also disclosed.

REFERENCES:
patent: 56-97266 (1981-08-01), None
Hemmi et al. (WO 97/47599), 1997. Abstract.

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