Urate oxidase activity protein, recombinant gene coding therefor

Details Urate oxidase activity protein, recombinant gene coding therefor Urate oxidase activity protein, recombinant gene coding therefor

1994-09-28

1996-07-30

Patterson, Jr., Charles L.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Oxidoreductase

4352402, 43525233, 4353201, 43525421, 536 232, C12N 906, C12N 1553

Patent

active

055410987

ABSTRACT:
The invention concerns a new urate oxidase activity protein which has the following sequence (SEQ ID NO:1): ##STR1## optionally preceded by a methionine, or in that it may present a degree of substantial homology with this sequence.
The invention is also aimed at medicines containing this protein as well as the genetic engineering implements to obtain it.

REFERENCES:
patent: 3810820 (1974-05-01), Labourer et al.
patent: 4431739 (1984-02-01), Riggs
Reddy et al., Proc. Natl. Acad. Sci., USA (1988), vol. 85, pp. 9081-9085.
Nielsen et al., Proc. Natl. Acad. Sci. USA (1983), vol. 80, pp. 5198-5202.
Mansson Rahemtulla et al., Biochemistry. vol. 27, pp. 233-239, issued Jan. 12, 1988.
Nakagawa et al., Biochem. Biophy. Res. Comm. vol. 127, No. 1, Feb. 1985, pp. 8-14.
Janson, Trends in Biotechnology, vol. 2, No. 2, 1984, pp. 31-38.
Berton et al., Journal Biol. Chem, vol. 264, No. 10, Apr. 1989, pp. 5564-5568.

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