Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-06-06
1998-10-06
O'Sullivan, Peter
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514 49, 514 50, 514256, 536 282, 536 2854, 544309, 544313, A61K 31505
Patent
active
058176640
ABSTRACT:
The present invention relates to a group of 5-substituted uracil derivatives which are inactivators of uracil reductase and which are particularily useful in cancer chemotherapy, especially in combination with antimetabolite antineoplastic agents such as 5-fluorouracil (5-FU).
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Porter David J. T.
Rahim Saad G.
Spector Thomas
Glaxo Wellcome Inc.
Hrubiec Robert T.
O'Sullivan Peter
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