Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1995-03-30
1997-10-07
Housel, James C.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 71, 435 795, 436169, 436172, 422 52, 422 8205, 422 56, G01N 3353, G01N 33537, G01N 33543
Patent
active
056746989
ABSTRACT:
The invention provides methods, compositions, and apparatus for performing sensitive detection of analytes, such as biological macromolecules and other analytes, by labeling a probe molecule with an up-converting label. The up-converting label absorbs radiation from an illumination source and emits radiation at one or more higher frequencies, providing enhanced signal-to-noise ratio and the essential elimination of background sample autofluorescence. The methods, compositions, and apparatus are suitable for the sensitive detection of multiple analytes and for various clinical and environmental sampling techniques.
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Dyer Mark J.
Faris Gregory W.
Kane James
Ng Steve Y.
Peppers Norman A.
Housel James C.
Portner Ginny Allen
SRI - International
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