Chemistry: analytical and immunological testing – Optical result – With fluorescence or luminescence
Patent
1995-06-07
1998-04-07
Soderquist, Arlen
Chemistry: analytical and immunological testing
Optical result
With fluorescence or luminescence
422 8205, 422 8209, 422 81, 356244, 356346, 2504581, 2504591, 436 52, 436 63, 436 81, 436524, 436518, G01N 2164, G01N 2162, G01N 2101
Patent
active
057364109
ABSTRACT:
The invention provides methods, compositions, and apparatus for performing sensitive detection of analytes, such as biological macromolecules and other analytes, by labeling a probe molecule with an up-converting label. The up-converting label absorbs radiation from an illumination source and emits radiation at one or more higher frequencies, providing enhanced signal-to-noise ratio and the essential elimination of background sample autofluorescence. The methods, compositions, and apparatus are suitable for the sensitive detection of multiple analytes and for various clinical and environmental sampling techniques.
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Dyer Mark J.
Faris Gregory W.
Kane James
Ng Steve Y.
Peppers Norman A.
Soderquist Arlen
SRI - International
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