Unusual retrotransposon from the yeast Candida albicans

Details Unusual retrotransposon from the yeast Candida albicans Unusual retrotransposon from the yeast Candida albicans

2006-03-28

2006-03-28

Guzo, David (Department: 1636)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S023400, C536S024100, C435S235100, C435S320100, C435S325000, C435S455000, C514S04400A

Reexamination Certificate

active

07019122

ABSTRACT:
TCa2 is a Tyl/copia retrotransposon from the pathogenic yeastCandida albicans. In contrast to other retrotransposons it can appear as an abundant, extrachromosomal double-stranded DNA molecule, called pCal. The invention relates to the isolation and characterisation of TCa2 and pCal together with its uses for inducing random mutagenesis in a genome, as a component of a transposable element and of an expression vector.

REFERENCES:
Mark L. Farman et al, MAGGY, a retrotransposon in the genome of the rice blast fungusMagnaporthe grisea, Mol Gen Genet 1996, 251:665-674, Springer-Verlag 1996.

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