Unsymmetrical bis-imides as anticancer agents

Details Unsymmetrical bis-imides as anticancer agents Unsymmetrical bis-imides as anticancer agents

1993-02-11

1994-10-25

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546 98, C07D22118, A61K 31435

Patent

active

053590708

ABSTRACT:
This invention relates to unsymmetrical bis-imide compounds, and pharmaceutically acceptable salts thereof, of the formula (i): ##STR1## including (R,R)-1-[2-(acenaphthene-5,6-dicarboximido) propylamino]-2-[2-(3-nitronaphthalene-1,8-dicarboximido) propylamino]ethane, processes for the preparation of such compounds, pharmaceutical compositions containing such compounds, and methods of using such compounds to treat cancer, particularly solid tumor carcinomas, in mammals.

REFERENCES:
patent: 4146720 (1979-03-01), Roldan et al.
patent: 4841052 (1989-06-01), Harnisch et al.
patent: 4874863 (1989-10-01), Brana et al.
patent: 4919848 (1990-04-01), Harnisch
patent: 5086059 (1992-02-01), Ardecky et al.
patent: 5206249 (1993-04-01), Sun
patent: 5206250 (1993-04-01), Sun
Mattern, Canc. & Metastasis Rev vol. 7, pp. 263-284 (1988).

Affiliated with

Also associated with

Rating

Unsymmetrical bis-imides as anticancer agents does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Unsymmetrical bis-imides as anticancer agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Unsymmetrical bis-imides as anticancer agents will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-136581