Unsaturated hydroxyalkylquinoline acids as leukotriene antagonis

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514314, 514826, 514924, 546162, 546167, 546171, 546172, 546174, 546175, 546176, A01N 4342, C07D21536, C07D21512

Patent

active

055654738

ABSTRACT:
Compounds having the formula I: ##STR1## are leukotriene antagonists and inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.

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