Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2005-01-21
2008-10-28
Epperson, Jon D. (Department: 1639)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C435S254200, C435S007100, C506S003000, C506S009000, C506S014000, C506S018000
Reexamination Certificate
active
07442773
ABSTRACT:
The present invention provides a universal peptide-binding scaffold. This scaffold is used to bind a target. The target can be a peptide or peptides of interest (for example, peptides associated with a disease state) or can represent the entire proteome. The target can be either protein fragments prepared by enzymatic digestion of the entire proteome or N- or C-terminal short sequences exposed by chemical denaturation of the entire proteome (unfolded proteins). The universal peptide-binding scaffold can be tailored to specifically bind a target using the methods described herein.
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Esteban Olga
Zhao Huimin
Epperson Jon D.
Greenlee Winner and Sullivan P.C.
Steele Amber D.
The Board of Trustees of The University of Illinois
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