Unitary one-piece sample mini-column

Measuring and testing – Liquid analysis or analysis of the suspension of solids in a... – Content or effect of a constituent of a liquid mixture

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422 70, G01N 3060

Patent

active

059182733

ABSTRACT:
This invention is directed to a unitary one-piece sample mini-column for a cassette chemical immobilization and treatment system for enabling the performance of various complex chemistries. The cassette assembly comprises a plurality of analyte sample columns ("mini-columns"), reagent wells containing pre-packaged reagents including powdered, microencapsulated, liquid or lyophillized reagents, analyte loading funnels, alignment mechanisms for the analyte sample columns, and a machine readable instruction code set for identfying a chemical treatment protocol. The mini-columns are improved columns having a high pressure interface capability to permit direct insertion of the mini-column into a high-pressure solvent line for use as a support column for HPLC analysis. The same chemistries may be performed at all sample mini-column addresses, or a separate, completely independent set of protocols may be defined for each address, or for each block of addresses pursuant to the instructions contained in the machine readable code on the cassette.

REFERENCES:
patent: 4046634 (1977-09-01), Mercer
patent: 4102179 (1978-07-01), Snell
patent: 4186607 (1980-02-01), Porter et al.
patent: 4285698 (1981-08-01), Otto et al.
patent: 5178832 (1993-01-01), Phillips et al.
patent: 5500071 (1996-03-01), Kaltenbach et al.
patent: 5529899 (1996-06-01), Wheelock et al.
patent: 5571410 (1996-11-01), Swedberg et al.
patent: 5589063 (1996-12-01), Sanford et al.
patent: 5645702 (1997-07-01), Witt et al.
patent: 5658413 (1997-08-01), Kaltenbach et al.
Nugent, K.D.; Burton, W.G.; Slattery, T.K.; Johnson, B.F.; Snyder, L.R. Jun. 29, 1988 J. Chrom. . 443, 381-397, Chrom Symp. 1371 "Seperation at Proteins by Reversed Phase High Performance Liquid Chromotography II. Optimitzing Sample Pretreatment and Mobile Phase Condition".
Hewlett-Packard Product Brochure: The HP G1004A Protein Chemistry Station minimizes sample handling and sample loss in HPLC and sequencing analysis. (23) 5091-5168E Nov. 1992, 4 pages.
Hewlett Packard Product Brochure: Increase lab productivity with the HP G005A Protein Sequencing System, (23-5091-5170E Nov. 1992) 7 pages.
Patent Abstract of Japan Grp. p. 819, vol. 13, No. 37 Abs pub. date Jan. 27, 1989.
(63-235858) "Selection of LC Eluting Conditions and Minicolumn" Ishide et al.

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