Unit dosage form of sparingly soluble medicaments

Details Unit dosage form of sparingly soluble medicaments Unit dosage form of sparingly soluble medicaments

1985-05-24

1988-01-05

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424497, 514172, 514176, A61K 914, A61K 3157, A61K 31565

Patent

active

047175699

ABSTRACT:
Pharmaceutical compositions of a polycyclic medicament having very low solubility in water and aqueous media comprise a plurality of beads, each bead comprising particles of finely divided medicament, which may have a particulate core or filler, bound together by a water soluble binder.

REFERENCES:
patent: 3328256 (1967-06-01), Gaunt
patent: 4361546 (1982-11-01), Stricker et al.
patent: 4367217 (1983-01-01), Gruber et al.
patent: 4389393 (1983-06-01), Schor et al.
patent: 4415547 (1983-11-01), Yu et al.
patent: 4438091 (1984-03-01), Gruber et al.
Chem. Abst. 103:128939(a) (1985)-Urtti et al.
Lachman et al., The Theory and Practice of Industrial Pharmacy, 2nd ed., pp. 456-459.

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