Unique T-lymphocyte line and products derived therefrom

Details Unique T-lymphocyte line and products derived therefrom Unique T-lymphocyte line and products derived therefrom

1983-01-06

1984-03-20

Schain, Howard E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260112B, 424 85, 424177, 435 68, 435172, 435240, 435241, 435948, C12P 2100, C12N 1500, C12R 191, C07G 700

Patent

active

044380321

ABSTRACT:
Human T-lymphoblast cell line, Proteinaceous products produced therefrom, messenger RNA and DNA expressing the proteinaceous products. A human T-lymphoblast cell line (Mo) maintained as a continuous culture constitutively produces proteins, including immune interferon, neutrophil migration inhibition factor, granulocyte-macrophage colony-stimulating activity and erythroid-potentiating activity, as well as other proteins produced by T-cells.

REFERENCES:
patent: 4338397 (1982-07-01), Gilbert
Saxon et al., Annals of Internal Medicine, (1978), 58:323-326.
Weisbart et al., Clin. Immunology & Immunopathology, (1979), 14:441-448.
Weisbart et al., J. Lab. Clin. Med., (1979), 93:622-626.
Lusis et al., In Viva and In Vitro Erythropoiesis, 1980, pp. 97-106.
Golde et al., Blood, (1978), 51:1068-1071.
Golde et al., PNAS, USA, (1980), 77:593-596.
Golde et al., Annals of Internal Medicine, (1980), 92:650-662.

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