Unique compositions of zwitterionic phospholipids and...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...

Reexamination Certificate

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C514S142000, C514S143000

Reexamination Certificate

active

06943155

ABSTRACT:
Compositions and methods for treating osteoporosis using the compositions are disclosed where the compositions have reduced GI toxicity and improved bio-availability and include a bisphosphonate and zwitterionic phospholipid.

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patent: WO 9904773 (1999-02-01), None
patent: WO 00 61111 (2000-10-01), None
International Journal of Pharmaceutics. vol. 162, No. 1-2, 1998, pp. 51-58 , XP001064839; N. Van Rooijen, A. Sanders: “ Manipulation of Kupffer cells by liposome encapsulated clodronate and propamidine-synergistic and antagonistic effects of liposomal phospholipids and drugs”.

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