Uniform spherical multilamellar liposomes of defined and adjusta

Details Uniform spherical multilamellar liposomes of defined and adjusta Uniform spherical multilamellar liposomes of defined and adjusta

1990-04-25

1992-12-22

Lovering, Richard D.

Plastic and nonmetallic article shaping or treating: processes

Encapsulating normally liquid material

Liquid encapsulation utilizing an emulsion or dispersion to...

424 11, 424450, 4284022, 436829, A61K 9127, B01J 1304

Patent

active

051732190

ABSTRACT:
An improved, rapid method for preparing substantially spherical multilamellar liposomes of a defined and adjustable size within the range of 2 to 100 micrometers, suitable for encapsulation and targeting of drugs.

REFERENCES:
patent: 3830750 (1974-08-01), Wellman
patent: 4235871 (1980-11-01), Papahadjopoulos et al.
patent: 4394372 (1983-07-01), Taylor
patent: 4752572 (1988-06-01), Sundberg et al.
Kim et al.: "Preparation of Multilamellar Vesicles of Defined Size-Distribution by Solvent-Spherule Evaporation", Biochimica et Biophysica Acta, 812 (1985) 793-801, Feb. 14, 1985.

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